A Mechanism-Based Population Pharmacokinetic Analysis Assessing the Feasibility of Efavirenz Dose Reduction to 400 mg in Pregnant Women

BACKGROUND: Reducing the dose of efavirenz can improve safety, reduce costs, and increase access for patients with HIV infection. According to the World Health Organization, a similar dosing strategy for all patient populations is desirable for universal roll-out; however, it remains unknown whether...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Clin Pharmacokinet
Main Authors: Schalkwijk, Stein, ter Heine, Rob, Colbers, Angela C., Huitema, Alwin D. R., Denti, Paolo, Dooley, Kelly E., Capparelli, Edmund, Best, Brookie M., Cressey, Tim R., Greupink, Rick, Russel, Frans G. M., Mirochnick, Mark, Burger, David M.
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2018
Teme:
Original Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182466/
https://ncbi.nlm.nih.gov/pubmed/29520730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-018-0642-9
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