A Mechanism-Based Population Pharmacokinetic Analysis Assessing the Feasibility of Efavirenz Dose Reduction to 400 mg in Pregnant Women

BACKGROUND: Reducing the dose of efavirenz can improve safety, reduce costs, and increase access for patients with HIV infection. According to the World Health Organization, a similar dosing strategy for all patient populations is desirable for universal roll-out; however, it remains unknown whether...

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Detalles Bibliográficos
Publicado en:Clin Pharmacokinet
Main Authors: Schalkwijk, Stein, ter Heine, Rob, Colbers, Angela C., Huitema, Alwin D. R., Denti, Paolo, Dooley, Kelly E., Capparelli, Edmund, Best, Brookie M., Cressey, Tim R., Greupink, Rick, Russel, Frans G. M., Mirochnick, Mark, Burger, David M.
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2018
Assuntos:
Original Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182466/
https://ncbi.nlm.nih.gov/pubmed/29520730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-018-0642-9
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