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Population Pharmacokinetics and Exposure-Response Relationships of Naldemedine
PURPOSE: To characterize population pharmacokinetic (PK) of naldemedine, to identify factors which influence naldemedine PK, and to evaluate their clinical relevancy based on exposure-response relationships. METHODS: A population PK model was developed with pooled naldemedine concentrations from hea...
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| Publicat a: | Pharm Res |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer US
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6182381/ https://ncbi.nlm.nih.gov/pubmed/30280262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-018-2501-7 |
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