The adhesion receptor GPR56 is activated by extracellular matrix collagen III to improve β-cell function

AIMS: G-protein coupled receptor 56 (GPR56) is the most abundant islet-expressed G-protein coupled receptor, suggesting a potential role in islet function. This study evaluated islet expression of GPR56 and its endogenous ligand collagen III, and their effects on β-cell function. METHODS: GPR56 and...

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Vydáno v:Cell Mol Life Sci
Hlavní autoři: Olaniru, Oladapo E., Pingitore, Attilio, Giera, Stefanie, Piao, Xianhua, Castañera González, Ramón, Jones, Peter M., Persaud, Shanta J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182347/
https://ncbi.nlm.nih.gov/pubmed/29855662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2846-4
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