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Disease-Associated Mutations Prevent GPR56-Collagen III Interaction
GPR56 is a member of the adhesion G protein-coupled receptor (GPCR) family. Mutations in GPR56 cause a devastating human brain malformation called bilateral frontoparietal polymicrogyria (BFPP). Using the N-terminal fragment of GPR56 (GPR56(N)) as a probe, we have recently demonstrated that collagen...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251603/ https://ncbi.nlm.nih.gov/pubmed/22238662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029818 |
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