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G protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and lamination
GPR56, an orphan G protein-coupled receptor (GPCR) from the family of adhesion GPCRs, plays an indispensable role in cortical development and lamination. Mutations in the GPR56 gene cause a malformed cerebral cortex in both humans and mice that resembles cobblestone lissencephaly, which is character...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150909/ https://ncbi.nlm.nih.gov/pubmed/21768377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104821108 |
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