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The adhesion receptor GPR56 is activated by extracellular matrix collagen III to improve β-cell function
AIMS: G-protein coupled receptor 56 (GPR56) is the most abundant islet-expressed G-protein coupled receptor, suggesting a potential role in islet function. This study evaluated islet expression of GPR56 and its endogenous ligand collagen III, and their effects on β-cell function. METHODS: GPR56 and...
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| Udgivet i: | Cell Mol Life Sci |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer International Publishing
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6182347/ https://ncbi.nlm.nih.gov/pubmed/29855662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2846-4 |
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