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Deacetylation of NAT10 by Sirt1 promotes the transition from rRNA biogenesis to autophagy upon energy stress

Anabolism and catabolism are tightly regulated according to the cellular energy supply. Upon energy stress, ribosomal RNA (rRNA) biogenesis is inhibited, and autophagy is induced. However, the mechanism linking rRNA biogenesis and autophagy is unclear. Here, we demonstrate that the nucleolar protein...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Liu, Xiaofeng, Cai, Shiying, Zhang, Chunfeng, Liu, Zhenzhen, Luo, Jianyuan, Xing, Baocai, Du, Xiaojuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182161/
https://ncbi.nlm.nih.gov/pubmed/30165671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky777
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