Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2

Maintenance of topological homeostasis is vital for gene expression and genome replication in all organisms. Similar to other circular genomes, also mitochondrial DNA (mtDNA) is known to exist in various different topological forms, although their functional significance remains unknown. We report h...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Hangas, Anu, Aasumets, Koit, Kekäläinen, Nina J, Paloheinä, Mika, Pohjoismäki, Jaakko L, Gerhold, Joachim M, Goffart, Steffi
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Nucleic Acid Enzymes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182158/
https://ncbi.nlm.nih.gov/pubmed/30169847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky793
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky