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Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2
Maintenance of topological homeostasis is vital for gene expression and genome replication in all organisms. Similar to other circular genomes, also mitochondrial DNA (mtDNA) is known to exist in various different topological forms, although their functional significance remains unknown. We report h...
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| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6182158/ https://ncbi.nlm.nih.gov/pubmed/30169847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky793 |
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