Ubiquitin modulates liquid-liquid phase separation of UBQLN2 via disruption of multivalent interactions

Under stress, certain eukaryotic proteins and RNA assemble to form membraneless organelles known as stress granules. The most well-studied stress granule components are RNA-binding proteins that undergo liquid-liquid phase separation (LLPS) into protein-rich droplets mediated by intrinsically-disord...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Cell
Autori principali: Dao, Thuy P., Kolaitis, Regina-Maria, Joo Kim, Hong, O’Donovan, Kevin, Martyniak, Brian, Colicino, Erica, Hehnly, Heidi, Taylor, J. Paul, Castañeda, Carlos A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181577/
https://ncbi.nlm.nih.gov/pubmed/29526694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.02.004
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi