Serum asunaprevir concentrations showing correlation with the extent of liver fibrosis as a factor inducing liver injuries in patients with genotype-1b hepatitis C virus receiving daclatasvir plus asunaprevir therapy

AIMS: Liver injury can occur during antiviral therapies with direct-acting antivirals (DAAs), potentially necessitating discontinuation of the therapies, with consequent worsening of the sustained viral response (SVR) rates, in patients with hepatitis C virus (HCV). To clarify the mechanisms involve...

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Vydáno v:PLoS One
Hlavní autoři: Uchida, Yoshihito, Naiki, Kayoko, Kouyama, Jun-ichi, Sugawara, Kayoko, Nakao, Masamitsu, Motoya, Daisuke, Inao, Mie, Nakayama, Nobuaki, Imai, Yukinori, Tomiya, Tomoaki, Mochida, Satoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181393/
https://ncbi.nlm.nih.gov/pubmed/30308053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205600
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