A Novel Simple Assay System to Quantify the Percent HCV-RNA Levels of NS5A Y93H Mutant Strains and Y93 Wild-Type Strains Relative to the Total HCV-RNA Levels to Determine the Indication for Antiviral Therapy with NS5A Inhibitors

AIM: Oral treatment with asunaprevir and daclatasvir has been reported to yield a SVR ratio of 80% in patients with genotype 1b HCV infection, however, treatment failure has been reported, especially in patients with HCV strains showing the NS5A-Y93H mutation at baseline. An assay system to detect s...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Uchida, Yoshihito, Kouyama, Jun-ichi, Naiki, Kayoko, Mochida, Satoshi
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232421/
https://ncbi.nlm.nih.gov/pubmed/25397971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112647
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki