Rapid, Sensitive, and Accurate Evaluation of Drug Resistant Mutant (NS5A-Y93H) Strain Frequency in Genotype 1b HCV by Invader Assay

Daclatasvir and asunaprevir dual oral therapy is expected to achieve high sustained virological response (SVR) rates in patients with HCV genotype 1b infection. However, presence of the NS5A-Y93H substitution at baseline has been shown to be an independent predictor of treatment failure for this reg...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Yoshimi, Satoshi, Ochi, Hidenori, Murakami, Eisuke, Uchida, Takuro, Kan, Hiromi, Akamatsu, Sakura, Hayes, C. Nelson, Abe, Hiromi, Miki, Daiki, Hiraga, Nobuhiko, Imamura, Michio, Aikata, Hiroshi, Chayama, Kazuaki
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470996/
https://ncbi.nlm.nih.gov/pubmed/26083687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130022
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