Rapid, Sensitive, and Accurate Evaluation of Drug Resistant Mutant (NS5A-Y93H) Strain Frequency in Genotype 1b HCV by Invader Assay

Daclatasvir and asunaprevir dual oral therapy is expected to achieve high sustained virological response (SVR) rates in patients with HCV genotype 1b infection. However, presence of the NS5A-Y93H substitution at baseline has been shown to be an independent predictor of treatment failure for this reg...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Yoshimi, Satoshi, Ochi, Hidenori, Murakami, Eisuke, Uchida, Takuro, Kan, Hiromi, Akamatsu, Sakura, Hayes, C. Nelson, Abe, Hiromi, Miki, Daiki, Hiraga, Nobuhiko, Imamura, Michio, Aikata, Hiroshi, Chayama, Kazuaki
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2015
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470996/
https://ncbi.nlm.nih.gov/pubmed/26083687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130022
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