Interferon alpha treatment stimulates interferon gamma expression in type I NKT cells and enhances their antiviral effect against hepatitis C virus

Interferon (IFN) inhibits hepatitis C virus (HCV) replication through up-regulation of intrahepatic IFN-stimulated gene expression but also through activation of host immune cells. In the present study, we analyzed the immune cell-mediated antiviral effects of IFN-α using HCV-infected mice. Urokinas...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Miyaki, Eisuke, Hiraga, Nobuhiko, Imamura, Michio, Uchida, Takuro, Kan, Hiromi, Tsuge, Masataka, Abe-Chayama, Hiromi, Hayes, C. Nelson, Makokha, Grace Naswa, Serikawa, Masahiro, Aikata, Hiroshi, Ochi, Hidenori, Ishida, Yuji, Tateno, Chise, Ohdan, Hideki, Chayama, Kazuaki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333814/
https://ncbi.nlm.nih.gov/pubmed/28253324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172412
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