Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia

Carbon monoxide (CO) at low, non-toxic concentrations has been previously demonstrated to exert anti-inflammatory protection in murine models of sickle cell disease (SCD). However CO delivery by inhalation, CO-hemoglobin infusion or CO-releasing molecules presents problems for daily CO administratio...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Belcher, John D., Gomperts, Edward, Nguyen, Julia, Chen, Chunsheng, Abdulla, Fuad, Kiser, Zachary M., Gallo, David, Levy, Howard, Otterbein, Leo E., Vercellotti, Gregory M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181332/
https://ncbi.nlm.nih.gov/pubmed/30308028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205194
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