Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing LRP4

During aging, acetylcholine receptor (AChR) clusters become fragmented and denervated at the neuromuscular junction (NMJ). Underpinning molecular mechanisms are not well understood. We showed that LRP4, a receptor for agrin and critical for NMJ formation and maintenance, was reduced at protein level...

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書誌詳細
出版年:J Neurosci
主要な著者: Zhao, Kai, Shen, Chengyong, Li, Lei, Wu, Haitao, Xing, Guanglin, Dong, Zhaoqi, Jing, Hongyang, Chen, Wenbing, Zhang, Hongsheng, Tan, Zhibing, Pan, Jinxiu, Xiong, Lei, Wang, Hongsheng, Cui, Wanpeng, Sun, Xiang-Dong, Li, Shihua, Huang, Xinping, Xiong, Wen-Cheng, Mei, Lin
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2018
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181315/
https://ncbi.nlm.nih.gov/pubmed/30171091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0860-18.2018
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