A Role of Low-Density Lipoprotein Receptor-Related Protein 4 (LRP4) in Astrocytic Aβ Clearance

Amyloid-β (Aβ) deposition occurs years before cognitive symptoms appear and is considered a cause of Alzheimer's disease (AD). The imbalance of Aβ production and clearance leads to Aβ accumulation and Aβ deposition. Increasing evidence indicates an important role of astrocytes, the most abundan...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Zhang, Hongsheng, Chen, Wenbing, Tan, Zhibing, Zhang, Lei, Dong, Zhaoqi, Cui, Wanpeng, Zhao, Kai, Wang, Hongsheng, Jing, Hongyang, Cao, Rangjuan, Kim, Chae, Safar, Jiri G., Xiong, Wen-Cheng, Mei, Lin
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2020
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343327/
https://ncbi.nlm.nih.gov/pubmed/32457076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0250-20.2020
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