Regulators of G-Protein Signaling (RGS) Proteins Promote Receptor Coupling to G-Protein-Coupled Inwardly Rectifying Potassium (GIRK) Channels

Regulators of G-protein signaling (RGS) proteins negatively modulate presynaptic μ-opioid receptor inhibition of GABA release in the ventrolateral periaqueductal gray (vlPAG). Paradoxically, we find that G-protein-coupled receptor (GPCR) activation of G-protein-gated inwardly rectifying K(+) channel...

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Publicat a:J Neurosci
Autors principals: McPherson, Kylie B., Leff, Emily R., Li, Ming-hua, Meurice, Claire, Tai, Sherrica, Traynor, John R., Ingram, Susan L.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181307/
https://ncbi.nlm.nih.gov/pubmed/30150362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0516-18.2018
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