The α6 Subunit-Containing GABA(A) Receptor: A Novel Drug Target for Inhibition of Trigeminal Activation

Novel treatments against migraine are an urgent medical requirement. α6 subunit-containing GABA(A) receptors (α6GABA(A)Rs) are expressed in trigeminal ganglia (TG), the hub of the trigeminal vascular system (TGVS) that is involved in the pathogenesis of migraine. Here we reveal an unprecedented role...

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Publicado no:Neuropharmacology
Main Authors: Fan, Pi-Chuan, Lai, Tzu-Hsuan, Hor, Chia Chun, Lee, Ming Tatt, Huang, Pokai, Sieghart, Werner, Ernst, Margot, Knutson, Daniel E, Cook, James, Chiou, Lih-Chu
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180911/
https://ncbi.nlm.nih.gov/pubmed/30016665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.07.017
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