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Age-Dependent Anti-migraine Effects of Valproic Acid and Topiramate in Rats
Background: Valproic acid (VPA) and topiramate (TPM), initially developed as antiepileptics, are approved for migraine prophylaxis in adults but not children. The differences in their antimigraine mechanism(s) by age remain unclear. Methods: A migraine model induced by intra-cisternal (i.c.) capsaic...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6167431/ https://ncbi.nlm.nih.gov/pubmed/30319425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01095 |
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