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Differentiation of Sendai Virus-Reprogrammed iPSC into β Cells, Compared with Human Pancreatic Islets and Immortalized β Cell Line

BACKGROUND: New sources of insulin-secreting cells are strongly in demand for treatment of diabetes. Induced pluripotent stem cells (iPSCs) have the potential to generate insulin-producing cells (iβ). However, the gene expression profile and secretory function of iβ still need to be validated in com...

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發表在:Cell Transplant
Main Authors: Pellegrini, Silvia, Manenti, Fabio, Chimienti, Raniero, Nano, Rita, Ottoboni, Linda, Ruffini, Francesca, Martino, Gianvito, Ravassard, Philippe, Piemonti, Lorenzo, Sordi, Valeria
格式: Artigo
語言:Inglês
出版: SAGE Publications 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180725/
https://ncbi.nlm.nih.gov/pubmed/30251567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0963689718798564
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