Thirty biologically interpretable clusters of transcription factors distinguish cancer type

BACKGROUND: Transcription factors are essential regulators of gene expression and play critical roles in development, differentiation, and in many cancers. To carry out their regulatory programs, they must cooperate in networks and bind simultaneously to sites in promoter or enhancer regions of gene...

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Bibliografiske detaljer
Udgivet i:BMC Genomics
Main Authors: Abrams, Zachary B., Zucker, Mark, Wang, Min, Asiaee Taheri, Amir, Abruzzo, Lynne V., Coombes, Kevin R.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180590/
https://ncbi.nlm.nih.gov/pubmed/30305013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5093-z
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