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Thirty biologically interpretable clusters of transcription factors distinguish cancer type

BACKGROUND: Transcription factors are essential regulators of gene expression and play critical roles in development, differentiation, and in many cancers. To carry out their regulatory programs, they must cooperate in networks and bind simultaneously to sites in promoter or enhancer regions of gene...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:BMC Genomics
Päätekijät: Abrams, Zachary B., Zucker, Mark, Wang, Min, Asiaee Taheri, Amir, Abruzzo, Lynne V., Coombes, Kevin R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180590/
https://ncbi.nlm.nih.gov/pubmed/30305013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5093-z
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