Transcriptional defects and reprogramming barriers in somatic cell nuclear reprogramming as revealed by single-embryo RNA sequencing

BACKGROUND: Nuclear reprogramming reinstates totipotency or pluripotency in somatic cells by changing their gene transcription profile. This technology is widely used in medicine, animal husbandry and other industries. However, certain deficiencies severely restrict the applications of this technolo...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Liu, Yong, Wu, Fengrui, Zhang, Ling, Wu, Xiaoqing, Li, Dengkun, Xin, Jing, Xie, Juan, Kong, Feng, Wang, Wenying, Wu, Qiaoqin, Zhang, Di, Wang, Rong, Gao, Shaorong, Li, Wenyong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180508/
https://ncbi.nlm.nih.gov/pubmed/30305014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5091-1
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