Transcriptional defects and reprogramming barriers in somatic cell nuclear reprogramming as revealed by single-embryo RNA sequencing

BACKGROUND: Nuclear reprogramming reinstates totipotency or pluripotency in somatic cells by changing their gene transcription profile. This technology is widely used in medicine, animal husbandry and other industries. However, certain deficiencies severely restrict the applications of this technolo...

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Vydáno v:BMC Genomics
Hlavní autoři: Liu, Yong, Wu, Fengrui, Zhang, Ling, Wu, Xiaoqing, Li, Dengkun, Xin, Jing, Xie, Juan, Kong, Feng, Wang, Wenying, Wu, Qiaoqin, Zhang, Di, Wang, Rong, Gao, Shaorong, Li, Wenyong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180508/
https://ncbi.nlm.nih.gov/pubmed/30305014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5091-1
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