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Defective Chromatin Structure in Somatic Cell Cloned Mouse Embryos

Epigenetic reprogramming plays a central role in the development of cloned embryos generated by somatic cell nuclear transfer, and it is believed that aberrant reprogramming leads to the abnormal development of most cloned embryos. Recent studies show that trimethylation of H3K27 (H3K27me3) contribu...

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Détails bibliographiques
Auteurs principaux: Zhang, Miao, Wang, Fengchao, Kou, Zhaohui, Zhang, Yu, Gao, Shaorong
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757202/
https://ncbi.nlm.nih.gov/pubmed/19602512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.011973
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