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Defective Chromatin Structure in Somatic Cell Cloned Mouse Embryos
Epigenetic reprogramming plays a central role in the development of cloned embryos generated by somatic cell nuclear transfer, and it is believed that aberrant reprogramming leads to the abnormal development of most cloned embryos. Recent studies show that trimethylation of H3K27 (H3K27me3) contribu...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757202/ https://ncbi.nlm.nih.gov/pubmed/19602512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.011973 |
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