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Genome-wide analysis of fitness data and its application to improve metabolic models
BACKGROUND: Synthetic biology and related techniques enable genome scale high-throughput investigation of the effect on organism fitness of different gene knock-downs/outs and of other modifications of genomic sequence. RESULTS: We develop statistical and computational pipelines and frameworks for a...
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| Publicado no: | BMC Bioinformatics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6180484/ https://ncbi.nlm.nih.gov/pubmed/30305012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2341-9 |
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