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Genome-wide analysis of fitness data and its application to improve metabolic models
BACKGROUND: Synthetic biology and related techniques enable genome scale high-throughput investigation of the effect on organism fitness of different gene knock-downs/outs and of other modifications of genomic sequence. RESULTS: We develop statistical and computational pipelines and frameworks for a...
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| 出版年: | BMC Bioinformatics |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6180484/ https://ncbi.nlm.nih.gov/pubmed/30305012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2341-9 |
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