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Oxidative dehalogenation and denitration by a flavin-dependent monooxygenase is controlled by substrate deprotonation

Enzymes that are capable of detoxifying halogenated phenols (HPs) and nitrophenols (NPs) are valuable for bioremediation and waste biorefining. HadA monooxygenase was found to perform dual functions of oxidative dehalogenation (hydroxylation plus halide elimination) and denitration (hydroxylation pl...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Pimviriyakul, Panu, Surawatanawong, Panida, Chaiyen, Pimchai
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180312/
https://ncbi.nlm.nih.gov/pubmed/30319747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01482e
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