Selective depletion of metastatic stem cells as therapy for human colorectal cancer

Selective elimination of metastatic stem cells (MetSCs) promises to block metastatic dissemination. Colorectal cancer (CRC) cells overexpressing CXCR4 display trafficking functions and metastasis‐initiating capacity. We assessed the antimetastatic activity of a nanoconjugate (T22‐GFP‐H6‐FdU) that se...

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Bibliografiske detaljer
Udgivet i:EMBO Mol Med
Main Authors: Céspedes, María Virtudes, Unzueta, Ugutz, Aviñó, Anna, Gallardo, Alberto, Álamo, Patricia, Sala, Rita, Sánchez‐Chardi, Alejandro, Casanova, Isolda, Mangues, María Antònia, Lopez‐Pousa, Antonio, Eritja, Ramón, Villaverde, Antonio, Vázquez, Esther, Mangues, Ramón
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180303/
https://ncbi.nlm.nih.gov/pubmed/30190334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201708772
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