Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations

Cerebral cavernous malformations (CCMs) are vascular lesions in the central nervous system causing strokes and seizures which currently can only be treated through neurosurgery. The disease arises through changes in the regulatory networks of endothelial cells that must be comprehensively understood...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Otten, Cécile, Knox, Jessica, Boulday, Gwénola, Eymery, Mathias, Haniszewski, Marta, Neuenschwander, Martin, Radetzki, Silke, Vogt, Ingo, Hähn, Kristina, De Luca, Coralie, Cardoso, Cécile, Hamad, Sabri, Igual Gil, Carla, Roy, Peter, Albiges‐Rizo, Corinne, Faurobert, Eva, von Kries, Jens P, Campillos, Mónica, Tournier‐Lasserve, Elisabeth, Derry, W Brent, Abdelilah‐Seyfried, Salim
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180302/
https://ncbi.nlm.nih.gov/pubmed/30181117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809155
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