MSK1 functions as a transcriptional coactivator of p53 in the regulation of p21 gene expression

Mitogen- and stress-activated kinase 1 (MSK1) is a chromatin kinase that facilitates activator-dependent transcription by altering chromatin structure through histone H3 phosphorylation. The kinase activity of MSK1 is activated by intramolecular autophosphorylation, which is initially triggered by t...

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Vydáno v:Exp Mol Med
Hlavní autoři: Ahn, Jihye, Lee, Jin Gyeong, Chin, Chuevin, In, Suna, Yang, Aerin, Park, Hee-Sung, Kim, Jaehoon, Park, Jeong Hyeon
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180136/
https://ncbi.nlm.nih.gov/pubmed/30305627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0160-8
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