Non-invasive imaging of disrupted protein homeostasis induced by proteasome inhibitor treatment using chemical exchange saturation transfer MRI

Proteasome inhibitors (PIs) are now standard of care for several cancers, and noninvasive biomarkers of treatment response are critically required for early patient stratification and treatment personalization. The present study evaluated whether chemical exchange (CEST) magnetic resonance imaging (...

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Vydáno v:Sci Rep
Hlavní autoři: Zhu, Yanan, Ramasawmy, Rajiv, Johnson, Sean Peter, Taylor, Valerie, Gibb, Alasdair, Pedley, R. Barbara, Chattopadhyay, Nibedita, Lythgoe, Mark F., Golay, Xavier, Bradley, Daniel, Walker-Samuel, Simon
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180115/
https://ncbi.nlm.nih.gov/pubmed/30305717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33549-x
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