Non-invasive imaging of disrupted protein homeostasis induced by proteasome inhibitor treatment using chemical exchange saturation transfer MRI

Proteasome inhibitors (PIs) are now standard of care for several cancers, and noninvasive biomarkers of treatment response are critically required for early patient stratification and treatment personalization. The present study evaluated whether chemical exchange (CEST) magnetic resonance imaging (...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhu, Yanan, Ramasawmy, Rajiv, Johnson, Sean Peter, Taylor, Valerie, Gibb, Alasdair, Pedley, R. Barbara, Chattopadhyay, Nibedita, Lythgoe, Mark F., Golay, Xavier, Bradley, Daniel, Walker-Samuel, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180115/
https://ncbi.nlm.nih.gov/pubmed/30305717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33549-x
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