Combining Developmental and Perturbation-Seq Uncovers Transcriptional Modules Orchestrating Neuronal Remodeling

Developmental neuronal remodeling is an evolutionarily conserved mechanism required for precise wiring of nervous systems. Despite its fundamental role in neurodevelopment and proposed contribution to various neuropsychiatric disorders, the underlying mechanisms are largely unknown. Here, we uncover...

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Udgivet i:Dev Cell
Main Authors: Alyagor, Idan, Berkun, Victoria, Keren-Shaul, Hadas, Marmor-Kollet, Neta, David, Eyal, Mayseless, Oded, Issman-Zecharya, Noa, Amit, Ido, Schuldiner, Oren
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6179959/
https://ncbi.nlm.nih.gov/pubmed/30300589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.09.013
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