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Combining Developmental and Perturbation-Seq Uncovers Transcriptional Modules Orchestrating Neuronal Remodeling

Developmental neuronal remodeling is an evolutionarily conserved mechanism required for precise wiring of nervous systems. Despite its fundamental role in neurodevelopment and proposed contribution to various neuropsychiatric disorders, the underlying mechanisms are largely unknown. Here, we uncover...

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Podrobná bibliografie
Vydáno v:Dev Cell
Hlavní autoři: Alyagor, Idan, Berkun, Victoria, Keren-Shaul, Hadas, Marmor-Kollet, Neta, David, Eyal, Mayseless, Oded, Issman-Zecharya, Noa, Amit, Ido, Schuldiner, Oren
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6179959/
https://ncbi.nlm.nih.gov/pubmed/30300589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.09.013
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