Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

Gene editing by CRISPR/Cas9 is commonly used to generate germline mutations or perform in vitro screens, but applicability for in vivo screening has so far been limited. Recently, it was shown that in Drosophila, Cas9 expression could be limited to a desired group of cells, allowing tissue-specific...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Meltzer, Hagar, Marom, Efrat, Alyagor, Idan, Mayseless, Oded, Berkun, Victoria, Segal-Gilboa, Netta, Unger, Tamar, Luginbuhl, David, Schuldiner, Oren
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506539/
https://ncbi.nlm.nih.gov/pubmed/31068592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10140-0
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