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Latrunculin A accelerates actin filament depolymerization in addition to sequestering actin monomers

Latrunculin A (LatA), a toxin from the red sea sponge Latrunculia magnifica, is the most widely used reagent to depolymerize actin filaments in experiments on live cells. LatA binds actin monomers and sequesters them from polymerization [1, 2]. Low concentrations of LatA result in rapid (tens of sec...

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Bibliografiske detaljer
Udgivet i:Curr Biol
Main Authors: Fujiwara, Ikuko, Zweifel, Mark E., Courtemanche, Naomi, Pollard, Thomas D.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6179359/
https://ncbi.nlm.nih.gov/pubmed/30270183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2018.07.082
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