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Indoleamine 2,3‐dioxygenase 1 in coronary atherosclerotic plaque enhances tissue factor expression in activated macrophages

BACKGROUND: Recent clinical studies have found that changes in the kynurenine (Kyn) pathway of tryptophan (Trp) metabolism are associated with cardiovascular events. However, the roles of the Kyn pathway on vascular wall thrombogenicity remain unknown. Indoleamine 2,3‐dioxygenase 1 (IDO1) is a rate‐...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Res Pract Thromb Haemost
Hauptverfasser: Watanabe, Yuki, Koyama, Shohei, Yamashita, Atsushi, Matsuura, Yunosuke, Nishihira, Kensaku, Kitamura, Kazuo, Asada, Yujiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178752/
https://ncbi.nlm.nih.gov/pubmed/30349892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12128
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