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Indoleamine 2,3‐dioxygenase 1 in coronary atherosclerotic plaque enhances tissue factor expression in activated macrophages

BACKGROUND: Recent clinical studies have found that changes in the kynurenine (Kyn) pathway of tryptophan (Trp) metabolism are associated with cardiovascular events. However, the roles of the Kyn pathway on vascular wall thrombogenicity remain unknown. Indoleamine 2,3‐dioxygenase 1 (IDO1) is a rate‐...

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Detalhes bibliográficos
Publicado no:Res Pract Thromb Haemost
Main Authors: Watanabe, Yuki, Koyama, Shohei, Yamashita, Atsushi, Matsuura, Yunosuke, Nishihira, Kensaku, Kitamura, Kazuo, Asada, Yujiro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178752/
https://ncbi.nlm.nih.gov/pubmed/30349892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12128
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