Indoleamine 2,3‐dioxygenase 1 in coronary atherosclerotic plaque enhances tissue factor expression in activated macrophages

BACKGROUND: Recent clinical studies have found that changes in the kynurenine (Kyn) pathway of tryptophan (Trp) metabolism are associated with cardiovascular events. However, the roles of the Kyn pathway on vascular wall thrombogenicity remain unknown. Indoleamine 2,3‐dioxygenase 1 (IDO1) is a rate‐...

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Bibliografiske detaljer
Udgivet i:Res Pract Thromb Haemost
Main Authors: Watanabe, Yuki, Koyama, Shohei, Yamashita, Atsushi, Matsuura, Yunosuke, Nishihira, Kensaku, Kitamura, Kazuo, Asada, Yujiro
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Original Articles: Thrombosis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178752/
https://ncbi.nlm.nih.gov/pubmed/30349892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12128
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