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Protein S K196E mutation reduces its cofactor activity for APC but not for TFPI
BACKGROUND: Protein S (PS) is an anticoagulant molecule that functions as a cofactor for activated protein C (APC) in the inactivation of activated coagulation factors Va (FVa) and VIIIa. It also serves as a cofactor for tissue factor pathway inhibitor (TFPI) in the efficient inhibition of factor Xa...
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| Publicat a: | Res Pract Thromb Haemost |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6178719/ https://ncbi.nlm.nih.gov/pubmed/30349894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12152 |
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