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HIT-Cas9: A CRISPR/Cas9 Genome-Editing Device under Tight and Effective Drug Control
The CRISPR/Cas9 enabled efficient gene editing in an easy and programmable manner. Controlling its activity in greater precision is desired for biomedical research and potential therapeutic translation. Here, we engrafted the CRISPR/Cas9 system with a mutated human estrogen receptor (ER(T2)), which...
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| Veröffentlicht in: | Mol Ther Nucleic Acids |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Gene & Cell Therapy
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6178243/ https://ncbi.nlm.nih.gov/pubmed/30312845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.08.022 |
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