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HIT-Cas9: A CRISPR/Cas9 Genome-Editing Device under Tight and Effective Drug Control

The CRISPR/Cas9 enabled efficient gene editing in an easy and programmable manner. Controlling its activity in greater precision is desired for biomedical research and potential therapeutic translation. Here, we engrafted the CRISPR/Cas9 system with a mutated human estrogen receptor (ER(T2)), which...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Zhao, Chen, Zhao, Yingze, Zhang, Jingfang, Lu, Jia, Chen, Li, Zhang, Yue, Ying, Yue, Xu, Junjun, Wei, Shixian, Wang, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178243/
https://ncbi.nlm.nih.gov/pubmed/30312845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.08.022
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