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The aged rhesus macaque manifests Braak stage III/IV Alzheimer’s-like pathology

INTRODUCTION: An animal model of late-onset Alzheimer’s disease is needed to research what causes degeneration in the absence of dominant genetic insults and why the association cortex is particularly vulnerable to degeneration. METHODS: We studied the progression of tau and amyloid cortical patholo...

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Vydáno v:Alzheimers Dement
Hlavní autoři: Paspalas, Constantinos D., Carlyle, Becky C., Leslie, Shannon, Preuss, Todd M., Crimins, Johanna L., Huttner, Anita J., van Dyck, Christopher H., Rosene, Douglas L., Nairn, Angus C., Arnsten, Amy F. T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178089/
https://ncbi.nlm.nih.gov/pubmed/29241829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2017.11.005
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