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Alzheimer’s-like pathology in aging rhesus macaques: Unique opportunity to study the etiology and treatment of Alzheimer’s disease

Although mouse models of Alzheimer’s disease (AD) have provided tremendous breakthroughs, the etiology of later onset AD remains unknown. In particular, tau pathology in the association cortex is poorly replicated in mouse models. Aging rhesus monkeys naturally develop cognitive deficits, amyloid pl...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Arnsten, Amy F. T., Datta, Dibyadeep, Leslie, Shannon, Yang, Sheng-Tao, Wang, Min, Nairn, Angus C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936707/
https://ncbi.nlm.nih.gov/pubmed/31871209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903671116
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