NK cell development in a human stem cell niche: KIR expression occurs independently of the presence of HLA class I ligands

The development of mature natural killer (NK) cells expressing killer cell immunoglobulin-like receptors (KIRs) depends on cell contact–dependent signals from nonhematopoietic cells. So far, detailed studies of this process have been hampered by the lack of an appropriate in vitro model. Here, human...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Zhao, Xiaoyi, Weinhold, Sandra, Brands, Jens, Hejazi, Maryam, Degistirici, Özer, Kögler, Gesine, Meisel, Roland, Uhrberg, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Immunobiology and Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177642/
https://ncbi.nlm.nih.gov/pubmed/30266820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018019059
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