The HLA-B −21 dimorphism impacts on NK cell education and clinical outcome of immunotherapy in acute myeloid leukemia

Natural killer (NK) cell function is regulated by inhibitory receptors, such as the family of killer immunoglobulin-like receptors (KIRs) and the NKG2A/CD94 heterodimer. These receptors recognize cognate HLA class I molecules on potential target cells, and recent studies imply that an HLA-B dimorphi...

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Detaylı Bibliyografya
Yayımlandı:Blood
Asıl Yazarlar: Hallner, Alexander, Bernson, Elin, Hussein, Brwa Ali, Ewald Sander, Frida, Brune, Mats, Aurelius, Johan, Martner, Anna, Hellstrand, Kristoffer, Thorén, Fredrik B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2019
Konular:
Immunobiology and Immunotherapy
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6440292/
https://ncbi.nlm.nih.gov/pubmed/30647027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-09-874990
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