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Reconstitution of a thermophilic Cu(+) importer in vitro reveals intrinsic high-affinity slow transport driving accumulation of an essential metal ion
Acquisition of the trace element copper (Cu) is critical to drive essential eukaryotic processes such as oxidative phosphorylation, iron mobilization, peptide hormone biogenesis, and connective tissue maturation. The Ctr1/Ctr3 family of Cu importers, first discovered in fungi and conserved in mammal...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6177576/ https://ncbi.nlm.nih.gov/pubmed/30131336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004802 |
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