A missense variant in SLC39A8 is associated with severe idiopathic scoliosis

Genetic factors predictive of severe adolescent idiopathic scoliosis (AIS) are largely unknown. To identify genetic variation associated with severe AIS, we performed an exome-wide association study of 457 severe AIS cases and 987 controls. We find a missense SNP in SLC39A8 (p.Ala391Thr, rs13107325)...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Haller, Gabe, McCall, Kevin, Jenkitkasemwong, Supak, Sadler, Brooke, Antunes, Lilian, Nikolov, Momchil, Whittle, Julia, Upshaw, Zachary, Shin, Jimann, Baschal, Erin, Cruchaga, Carlos, Harms, Matthew, Raggio, Cathleen, Morcuende, Jose A., Giampietro, Philip, Miller, Nancy H., Wise, Carol, Gray, Ryan S., Solnica-Krezel, Lila, Knutson, Mitchell, Dobbs, Matthew B., Gurnett, Christina A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177404/
https://ncbi.nlm.nih.gov/pubmed/30301978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06705-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados